Getting to personalized cancer medicine
نویسندگان
چکیده
منابع مشابه
Human Cancer Modeling: Recapitulating Tumor Heterogeneity Towards Personalized Medicine
Despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. Chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...
متن کاملLimits to Personalized Cancer Medicine.
Rapid advances in the molecular characterization of tumors, including complete gene sequencing of multiple cancers in the Cancer Genome Project, have led to an increased understanding of the molecular pathways that underlie cancer. These genomic changes differentiate tumors from normal tissues, permitting targeted treatments for several types of tumor and thereby extending survival and improvin...
متن کاملHuman Cancer Modeling: Recapitulating Tumor Heterogeneity Towards Personalized Medicine
Despite diagnostic, preventive and therapeutic advances, growing incidence of cancer and high rate of mortality among patients affected by specific cancer types indicate current clinical measures are not ideally useful in eradicating cancer. Chemoresistance and subsequent disease relapse are believed to be mainly driven by the cell-molecular heterogeneity of human tumors that necessitates perso...
متن کاملBreast Cancer Personalized Medicine
W.B.C. is Special Editor of the Breast Cancer Theme Issue. Personalized medicine, individualized medicine, and precision medicine are interchangeable terms that describe an approach to the treatment of disease that harnesses our understanding of the molecular basis and mechanisms of a given disease and matches appropriate therapeutic interventions. Breast cancer represents a diverse collection ...
متن کاملPersonalized Medicine and Cancer
Cancer is one of the leading causes of death in the United States, and more than 1.5 million new cases and more than 0.5 million deaths were reported during 2010 in the United States alone. Following completion of the sequencing of the human genome, substantial progress has been made in characterizing the human epigenome, proteome, and metabolome; a better understanding of pharmacogenomics has ...
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ژورنال
عنوان ژورنال: Cancer
سال: 2007
ISSN: 0008-543X,1097-0142
DOI: 10.1002/cncr.22966